A convergence of empirical evidence and spiritual philosophies suggests that long-term well-being improvement may be more readily achieved by transforming consciousness than by altering external events and circumstances. Approaches to improving the quality of consciousness include spiritual disciplines, Western psychological therapies, and flow activities (activities that provide challenges corresponding to skill levels such that anxiety and boredom are prevented and attention is focused entirely on the present task). These approaches to transforming consciousness may be thought of as consciousness self-control techniques (CSCT's). Choosing a CSCT may, for many, be the first step to improving well-being. CSCT selection strategies have been suggested, but no suggestions are evidence-based. The lack of evidence-based approaches to CSCT selection is problematic for mental health and wellness professionals who understand the relationship between conscious self-control and well-being, who are committed to promoting well-being, and who appreciate the importance of basing recommendations on evidence. Though difficult to conduct, research suggesting which CSCT may be most effective for whom may be valuable. It may prevent individuals from investing time and energy in a CSCT that is not maximally beneficial, may motivate individuals to try a CSCT of proven efficacy, and may help health care professionals determine the most effective ways to promote well-being.